A special weather statement is in effect for Belleville, Quinte West, Northumberland County, Cobourg and Colborne.
Environment Canada says the region can expect another significant rainfall Friday.
Rain, heavy at times, will move into Central and Eastern Ontario overnight and continue into Friday evening. Total rainfall amounts of 25 to 40 millimetres are forecast by late Friday night.
Flood messaging is in effect for much of Central and Eastern Ontario.
This heavy rain is associated with a Texas low that will track across Southern Ontario on Friday.